|
| Status |
Public on Jan 16, 2014 |
| Title |
Circulating miRNAs spectra in plasma of multiple myeloma patients compared with healthy individuals |
| Organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
|
| Summary |
MicroRNAs (miRNAs) are a class of small non-coding single-stranded RNAs whose dysregulation of expression plays an important role in cancer development. Circulating miRNAs are novel biomarkers in several cancers. Thus, we explored whether the miRNAs in plasma could be useful clinical biomarkers for multiple myeloma (MM) patients.
The expression levels of four miRNAs in plasma were upregulated while eight miRNAs were downregulated in MM patients compared with healthy controls according to microarray.
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| |
|
| Overall design |
MiRNA microarray was conducted to determine deregulated miRNAs in plasma of 9 MM patients and 7 healthy controls.
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| |
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| Contributor(s) |
Chen L, Qu X |
| Citation(s) |
25216866 |
| |
| Submission date |
Jan 16, 2014 |
| Last update date |
Jun 19, 2018 |
| Contact name |
Lijuan Chen |
| Organization name |
the First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital
|
| Street address |
300 Guangzhou Road
|
| City |
Nanjing |
| ZIP/Postal code |
210029 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL16770 |
Agilent-031181 Unrestricted_Human_miRNA_V16.0_Microarray (miRBase release 16.0 miRNA ID version) |
|
| Samples (16)
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| Relations |
| BioProject |
PRJNA235313 |
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