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Status |
Public on Mar 27, 2014 |
Title |
Genome-wide maps of HIF1a binding sites in ccRCC cell line under hypoxia condition |
Organism |
Homo sapiens |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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Summary |
We report the application of chromatin immunoprecipitation and next generation sequencing technology for HIF1a binding sites at genome wide level in a RCC (renal cell carcinoma) cell line under hypoxia conditions. We found HIF1a binding sites in Caki-2 cell line under hypoxia conditions. Especially, we found HIF1a bind to SPOP under hypoxia condition, which was further validated.
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Overall design |
Examination of HIF1a binding sites in Caki-2 cell line under hypoxia condition
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Contributor(s) |
Li G, Zhang J |
Citation(s) |
24656772 |
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Submission date |
Jan 23, 2014 |
Last update date |
May 15, 2019 |
Contact name |
Jing Zhang |
E-mail(s) |
henry.jingzhang@gmail.com
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Organization name |
Columbia University Medical Center
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Street address |
1130 St Nicholas Ave ICRC, room403
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City |
Beijing |
ZIP/Postal code |
10032 |
Country |
USA |
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Platforms (1) |
GPL13393 |
AB SOLiD 4 System (Homo sapiens) |
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Samples (1) |
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Relations |
BioProject |
PRJNA236347 |
SRA |
SRP035639 |