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Status |
Public on Feb 10, 2015 |
Title |
Age-dependent gene and protein expression following transection of neonatal spinal cord of Monodelphis domestica (South American Grey Short-tailed opossum) |
Organism |
Monodelphis domestica |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
In the present study we investigated the genome and the proteome in the segment of cord rostral to the site of injury following a complete spinal cord transection in opossums at an age when axonal growth across a lesion and substantially normal locomotor development occur (postnatal day 7, P7) and compared this with an older age when no axon growth can be seen, but nevertheless a demonstrable body weight-bearing locomotion is present (P28, Wheaton et al, 2011).
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Overall design |
7 RNA-seq samples, consisting of 2 biological replicates of controls at day 8, 1 control sample at day 29, and 2 biological replicates each from injured animals at days 8 and 29.
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Contributor(s) |
Saunders NR, Noor NM, Dziegielewska KM, Wheaton BN, Liddelow SA, Steer DL, Ek CJ, Habgood MD, Wakefield M, Lindsay H, Truettner J, Miller RD, Smith AI, Dietrich WD |
Citation(s) |
24914927 |
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Submission date |
Feb 09, 2014 |
Last update date |
May 15, 2019 |
Contact name |
Norman Saunders |
E-mail(s) |
n.saunders@unimelb.edu.au
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Organization name |
University of Melbourne
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Department |
Pharmacology and Therapeutics
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Lab |
Developmental Neuroscience and Neurotrauma
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Street address |
Grattan Street, Parkville
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City |
Melbourne |
State/province |
VIC |
ZIP/Postal code |
3010 |
Country |
Australia |
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Platforms (1) |
GPL17258 |
Illumina Genome Analyzer II (Monodelphis domestica) |
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Samples (7)
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Relations |
BioProject |
PRJNA237723 |
SRA |
SRP036951 |