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| Status |
Public on Sep 05, 2014 |
| Title |
DNA methylation analysis during in vitro myogenic differentiation |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by genome tiling array
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| Summary |
DNA methylation has been considered to play an important role in myogenic differentiation. In terminal differentiation of myoblasts, a chronological pattern of DNA methylation changes has been poorly understood. Using Infinium HumanMethylation450 BeadChips, we obtained and evaluated the genome-wide DNA methylation profiles of human myoblast differentiation in vitro.
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| Overall design |
DNA methylation profiles of human myoblasts (day1, day3, day8, day15), human mesenchymal stem cells (1 sample) and human skeletal muscle tissues (2 samples) were obtained using Infinium HumanMethylation450 BeadChips (Illumina).
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| |
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| Contributor(s) |
Miyata K, Miyata T, Nakabayashi K, Asahara H |
| Citation(s) |
25190712 |
| |
| Submission date |
Mar 04, 2014 |
| Last update date |
Mar 22, 2019 |
| Contact name |
Kazuhiko Nakabayashi |
| E-mail(s) |
nakabaya-k@ncchd.go.jp
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| Organization name |
National Research Institute for Child Health and Development
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| Department |
Department of Maternal-Fetal Biology
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| Street address |
2-10-1 Okura
|
| City |
Setagaya |
| State/province |
Tokyo |
| ZIP/Postal code |
157-8535 |
| Country |
Japan |
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| Platforms (1) |
| GPL13534 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482) |
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| Samples (7)
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| GSM1339341 |
myoblasts 15 days after myogenic stimuli |
| GSM1339342 |
human mesenchymal stem cells |
| GSM1339343 |
skeletal muscle tissue from healthy individual 1 |
| GSM1339344 |
skeletal muscle tissue from healthy individual 2 |
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| Relations |
| BioProject |
PRJNA240072 |
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