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| Status |
Public on Mar 26, 2014 |
| Title |
Identification of genes associated with TGF-beta/Smad3-mediated renal inflammation and fibrosis by RNA sequencing |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
In this study, we employed high-throughput RNA sequencing (RNA-Seq) to identify the Smad3-dependent lncRNAs related to renal inflammation and fibrosis in Smad3 knockout (KO) mouse models of unilateral ureteral obstructive nephropathy (UUO) and immunologically-induced anti-glomerular basement membrane glomerulonephritis (anti-GBM GN).
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| Overall design |
12 kidney tissue samples of Smad3 KO/WT mice from normal control, UUO at day 5 or anti-GBM GN at day 10 models (n=2 in each group) for whole transcriptome RNA-sequencing.
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| |
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| Contributor(s) |
Zhou Q, Lan H |
| Citation(s) |
24262754, 26648110 |
| BioProject |
PRJNA223210 |
| |
| Submission date |
Mar 11, 2014 |
| Last update date |
Jul 26, 2019 |
| Contact name |
Qin ZHOU |
| E-mail(s) |
zhouqin001994@163.com
|
| Organization name |
Li Ka Shing Institute of Health Sciences
|
| Department |
The Chinese University of Hong Kong
|
| Street address |
Room 601, Inflammation Lab. Li Ka Shing Institute of Medical Building, Shatin, NT
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| City |
Hongkong |
| ZIP/Postal code |
999077 |
| Country |
China |
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| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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| Samples (12)
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| Relations |
| SRA |
SRP040560 |
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