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Status |
Public on May 01, 2017 |
Title |
Comparative expression of bone metastasis clones and its parental cells on Chinese lung adenocarcinoma cell line SPC-A-1 and human larger cell lung cancer cell line NCI-H460 by cDNA array. |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Chinese lung adenocarcinoma cancer cells (SPC-A-1) and human larger cell lung cancer cells (NCI-H460) were injected into left cardiac ventricle of nude mice for bone metastases model, respectively. Bone metastatic lesions were detected by bone scintigraphy with 99mTc-methylene diphophonate, removed bone metastatic lesions for cell primary culture, chromosome analysis for determine the bone metastatic cells have a characterization of unchanged humanization, in the anesthesia death mice. Through eight in vivo ~ in vitro selections, the 4th, 8th generation cells of SPC-A-1, 8th generation cells of NCI-H460 and their parental cells were used for microarray analysis, respectively.
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Overall design |
Bone metastatic clones 4th and/or 8th generation SPC-A-1 vs. SPC-A-1, 8th generation NCI-H460 vs. NCI-H460, respectively. Biological replicates: one replicate for every group, independently grown and harvested. One replicate per array.
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Contributor(s) |
Yang S, Su J, Shi M, Fan L, Jin X, Zhao L, Xie W |
Citation missing |
Has this study been published? Please login to update or notify GEO. |
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Submission date |
May 07, 2014 |
Last update date |
May 02, 2017 |
Contact name |
Shu Yang |
Organization name |
GEORGE WASHINGTON UNIV
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Street address |
SEH, Suite 8840, 800 22nd Street NW
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City |
Washington, DC |
State/province |
District of Columbia |
ZIP/Postal code |
20052 |
Country |
USA |
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Platforms (1) |
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Samples (3) |
GSM1382091 |
Bone metastatic clones 4th generation SPC-A-1 |
GSM1382092 |
Bone metastatic clones 8th generation SPC-A-1 |
GSM1382093 |
Bone metastatic clones 8th generation NCI-H460 |
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Relations |
BioProject |
PRJNA246395 |
Supplementary file |
Size |
Download |
File type/resource |
GSE57402_RAW.tar |
2.9 Mb |
(http)(custom) |
TAR (of TXT) |
Processed data included within Sample table |
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