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Series GSE57402 Query DataSets for GSE57402
Status Public on May 01, 2017
Title Comparative expression of bone metastasis clones and its parental cells on Chinese lung adenocarcinoma cell line SPC-A-1 and human larger cell lung cancer cell line NCI-H460 by cDNA array.
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Chinese lung adenocarcinoma cancer cells (SPC-A-1) and human larger cell lung cancer cells (NCI-H460) were injected into left cardiac ventricle of nude mice for bone metastases model, respectively. Bone metastatic lesions were detected by bone scintigraphy with 99mTc-methylene diphophonate, removed bone metastatic lesions for cell primary culture, chromosome analysis for determine the bone metastatic cells have a characterization of unchanged humanization, in the anesthesia death mice. Through eight in vivo ~ in vitro selections, the 4th, 8th generation cells of SPC-A-1, 8th generation cells of NCI-H460 and their parental cells were used for microarray analysis, respectively.
 
Overall design Bone metastatic clones 4th and/or 8th generation SPC-A-1 vs. SPC-A-1, 8th generation NCI-H460 vs. NCI-H460, respectively. Biological replicates: one replicate for every group, independently grown and harvested. One replicate per array.
 
Contributor(s) Yang S, Su J, Shi M, Fan L, Jin X, Zhao L, Xie W
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date May 07, 2014
Last update date May 02, 2017
Contact name Shu Yang
Organization name GEORGE WASHINGTON UNIV
Street address SEH, Suite 8840, 800 22nd Street NW
City Washington, DC
State/province District of Columbia
ZIP/Postal code 20052
Country USA
 
Platforms (1)
GPL4381 UGI Human 14112 V1.0
Samples (3)
GSM1382091 Bone metastatic clones 4th generation SPC-A-1
GSM1382092 Bone metastatic clones 8th generation SPC-A-1
GSM1382093 Bone metastatic clones 8th generation NCI-H460
Relations
BioProject PRJNA246395

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE57402_RAW.tar 2.9 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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