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| Status |
Public on May 02, 2020 |
| Title |
Evolutionary changes in cis regulation are associated with altered chromatin activity and gene expression levels in the Drosophila eye development (RNA-Seq) |
| Organisms |
Drosophila ananassae; Drosophila melanogaster; Drosophila mojavensis; Drosophila pseudoobscura; Drosophila simulans; Drosophila virilis; Drosophila yakuba; Drosophila willistoni |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Expression profiling by high-throughput sequencing (RNA-seq) across eight WT Drosophila species - D. melanogaster, D. simulans, D. yakuba, D. ananassae, D. pseudoobscura, D. willistoni, D. mojavensis and D. virilis - and three tissues, namely, brain, eye-antennal and imaginal discs, at the stage of third instar larvae.
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| Overall design |
By the use of Ornstein-Uhlenbeck methods, we assess the evolutionary forces acting on regulatory elements (cis-level), chromatin activity and gene expression across Drosophila eye-antennal imaginal discs at the stage of third instar larvae.
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| Contributor(s) |
Naval-Sánchez M, Potier D, Christiaens V, Hulselmans G, Aerts S |
| Citation missing |
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| |
| Submission date |
Jul 23, 2014 |
| Last update date |
May 03, 2020 |
| Contact name |
Stein Aerts |
| Organization name |
KULeuven
|
| Department |
Center for Human Genetics
|
| Lab |
Laboratory of Computational Biology
|
| Street address |
Herestraat 49
|
| City |
Leuven |
| ZIP/Postal code |
3000 |
| Country |
Belgium |
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| Platforms (8)
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| GPL13304 |
Illumina HiSeq 2000 (Drosophila melanogaster) |
| GPL13306 |
Illumina HiSeq 2000 (Drosophila simulans) |
| GPL13307 |
Illumina HiSeq 2000 (Drosophila yakuba) |
| GPL13309 |
Illumina HiSeq 2000 (Drosophila ananassae) |
| GPL13310 |
Illumina HiSeq 2000 (Drosophila pseudoobscura) |
| GPL13311 |
Illumina HiSeq 2000 (Drosophila mojavensis) |
| GPL13313 |
Illumina HiSeq 2000 (Drosophila virilis) |
| GPL14359 |
Illumina HiSeq 2000 (Drosophila willistoni) |
|
| Samples (27)
|
| GSM1444009 |
RNA_Dmel_RAL-208_EA: RNA_seq_eye-antennal_imaginal_disc_wild-type [RAL-208] |
| GSM1444010 |
RNA_Dmel_CS_EA: RNA_seq_eye-antennal_imaginal_disc_wild-type [CantonS] |
| GSM1444011 |
RNA_Dsim_EA |
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| Relations |
| BioProject |
PRJNA256000 |
| SRA |
SRP044761 |
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