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Series GSE60339 Query DataSets for GSE60339
Status Public on Aug 01, 2016
Title Impact of E2 ubiquitin conjugating activity of MUC1 on gene expression
Organism Homo sapiens
Experiment type Expression profiling by array
Summary We identified a novel E2 ubiquitin conjugating activity within the C-terminus domain of MUC1. To determine if E2 ubiquitin conjugating activity of MUC1 is responsible for regulating expression of oncogenic genes we isolated RNA from vector control cells, MUC1 wildtype overexpression cells, and cells that express a serine mutant lacking E2 activity.
 
Overall design RNA was isolated from each of the 3 cell lines, S2013.Neo, S2013.MUC1-WT, and S2013.MUC1-Ser. Gene expression was analyzed by spotted microarray and the differences in gene expression were calculated between the cell lines
 
Contributor(s) Brown RB, Hanson RL, Grunkemeyer JA, Fink DM, Radhakrishnan P, Mohr AM, Grandgenett PM, Singh PK, Hollingsworth MA
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Submission date Aug 12, 2014
Last update date Aug 02, 2016
Contact name Ryan Hanson
E-mail(s) ryan.hanson@unmc.edu
Organization name University of Nebraska Medical Center
Department Eppley
Lab Dr. Michael A Hollingsworth
Street address 42nd and Emile
City Omaha
State/province Nebraska
ZIP/Postal code 68198
Country USA
 
Platforms (1)
GPL13693 Phalanx Human OneArray® v5
Samples (3)
GSM1473441 S2013.MUC1-WT vs S2013.Neo
GSM1473443 S2013.MUC1-WT vs S2013.MUC1-Ser
GSM1473446 S2013.MUC1-Ser vs S2013.Neo
Relations
BioProject PRJNA258057

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE60339_RAW.tar 10.7 Mb (http)(custom) TAR (of GPR)
Processed data included within Sample table

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