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Status |
Public on May 14, 2015 |
Title |
Distribution of H3K27me2, dUTX, and histone H3 in Sg4 cells |
Organism |
Drosophila melanogaster |
Experiment type |
Genome binding/occupancy profiling by genome tiling array
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Summary |
PcG protein complex PRC2 is a methyltransferase specific for histone H3 lysine27, and H3K27me3 is essential for stable transcription silencing. Less well known but quantitatively much more important is the genome-wide role of PRC2 that dimethylates more than half of total H3K27. Here we have determined genomic distributions of H3K27me2, dUTX, and histone H3 in cultured Drosophila Sg4 cells by hybridization of ChIP products with tiling microarrays.
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Overall design |
Genomic distributions of H3K27me2, dUTX, and histone H3 in cultured Drosophila Sg4 cells by hybridization of ChIP products with tiling microarrays
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Contributor(s) |
Schwartz YB, Kahn TG, Pirrotta V |
Citation(s) |
25986499 |
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Submission date |
Sep 09, 2014 |
Last update date |
Jul 13, 2015 |
Contact name |
Hun-Goo Lee |
Organization name |
Mass General Hospital
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Department |
Molecular Biology
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Lab |
Jeannie T Lee Lab
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Street address |
185 Cambridge St
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City |
Boston |
State/province |
MA |
ZIP/Postal code |
02114 |
Country |
USA |
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Platforms (1) |
GPL11397 |
[Dm35b_MF] Affymetrix Drosophila Tiling 1.0F Array |
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Samples (8)
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This SubSeries is part of SuperSeries: |
GSE61280 |
Genome-wide activities of Polycomb complexes |
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Relations |
BioProject |
PRJNA260610 |