|
| Status |
Public on Dec 01, 2017 |
| Title |
Targeted CpG island methylation in human pluripotent stem cells |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
In our manuscript, we describe novel methodologies for bidirectional DNA methylation editing at targeted genomic loci through homologous recombination (HR) in human pluripotent stem cells. In order to gain insights on the applicability of these methodologies towards modeling epigenetic alterations, as well as for the development of platforms for cell transplantation upon epigenetic correction.
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| |
|
| Overall design |
Analysis of targeted CpG island methylation
|
| |
|
| Contributor(s) |
Takahashi Y, Shokhirev MN, Benner C |
| Citation(s) |
28473583 |
| Submission date |
Dec 08, 2014 |
| Last update date |
Mar 28, 2022 |
| Contact name |
April Elizabeth Williams |
| E-mail(s) |
apriljack06@gmail.com, awilliams@salk.edu
|
| Phone |
7345461645
|
| Organization name |
Salk Institute for Biological Studies
|
| Department |
IGC
|
| Street address |
10010 N Torrey Pines Rd
|
| City |
San Diego |
| State/province |
California |
| ZIP/Postal code |
92037 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
|
| Samples (29)
|
|
| Relations |
| BioProject |
PRJNA269567 |
| SRA |
SRP050889 |
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