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| Status |
Public on Jun 16, 2015 |
| Title |
TRPM7 maintains mesenchymal phenotype of breast cancer cells by tensional regulation of SOX4 (TRPM7 shRNA) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Analysis of the effect of shRNA-mediated knockdown of TRPM7 on gene expression levels in MDA-MB-231 human breast cancer cells.
Results were used for the identification of so-called epithelial-mesenchymal transcription factors that were affected by TRPM7 knockdown and for the analysis of overlapping up- and downregulated genes in shT7#1 + shSOX4#1 MDA-MB-231 cells
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| Overall design |
Total RNA isolated from MDA-MB-231 breast cancer cells transduced with a scrambled shRNA (shCntrl) or TRPM7 shRNA (shT7#1)
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| Contributor(s) |
Kuipers AJ, Middelbeek J, Poelmans G, Klarenbeek J, Jalink K, van Leeuwen FN |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Dec 08, 2014 |
| Last update date |
Jan 28, 2016 |
| Contact name |
Arthur J Kuipers |
| E-mail(s) |
arthur.kuipers@radboudumc.nl
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| Organization name |
Radboudumc
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| Street address |
PO Box 9101
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| City |
Nijmegen |
| ZIP/Postal code |
6500 HB |
| Country |
Netherlands |
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| Platforms (1) |
| GPL10904 |
Illumina HumanHT-12 V4.0 expression beadchip (gene symbol) |
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| Samples (4)
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| This SubSeries is part of SuperSeries: |
| GSE63958 |
TRPM7 maintains mesenchymal phenotype of breast cancer cells by tensional regulation of SOX4 |
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| Relations |
| BioProject |
PRJNA269600 |
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