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| Status |
Public on Jan 13, 2015 |
| Title |
Microarray analysis on livers of young Nile rats fed palm fruit juice |
| Platform organism |
Mus musculus |
| Sample organism |
Arvicanthis niloticus |
| Experiment type |
Expression profiling by array
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| Summary |
Microarray analysis on livers of young (three weeks old) Nile rats (Arvicanthis niloticus) fed with either a high carbohydrate diet only (percentage energy from carbohydrate:fat:protein = 70:10:20, 16.7 kJ/g) or a high carbohydrate diet supplemented with palm fruit juice (PFJ) (415 ml of 13000 ppm gallic acid equivalent (GAE) for a final concentration of 5.4 g GAE per kg diet or 2.7 g per 2000 kcal)
PFJ (415 ml of 13000 ppm gallic acid equivalent (GAE) for a final concentration of 5.4 g GAE per kg diet or 2.7 g per 2000 kcal) was supplemented to young Nile rats (Arvicanthis niloticus) given a high carbohydrate diet (percentage energy from carbohydrate:fat:protein = 70:10:20, 16.7 kJ/g) to observe for possible anti-diabetic effects. Livers were harvested four weeks after the feeding regimen for gene expression studies. Results from the microarray data analysis carried out show that rats given PFJ had down-regulated insulin signalling, consistent with anti-diabetic effects observed in vivo.
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| Overall design |
Total RNA obtained from livers of young Nile rats (Arvicanthis niloticus) given PFJ in a high carbohydrate diet (four weeks after the feeding regimen) were compared to controls (three replicates in the treatment group versus four replicates in the control group)
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| Contributor(s) |
Leow S, Hayes KC, Sambanthamurthi R |
| Citation(s) |
27795741 |
| |
| Submission date |
Jan 12, 2015 |
| Last update date |
Dec 30, 2016 |
| Contact name |
Soon-Sen Leow |
| Organization name |
Malaysian Palm Oil Board
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| Street address |
No. 6, Persiaran Institusi, Bandar Baru Bangi
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| City |
Kajang |
| State/province |
Selangor |
| ZIP/Postal code |
43000 |
| Country |
Malaysia |
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| Platforms (1) |
| GPL8389 |
Illumina Mouse-8 Expression BeadChip |
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| Samples (7)
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| Relations |
| BioProject |
PRJNA272437 |
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