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| Status |
Public on Aug 09, 2016 |
| Title |
SOX7-enforced expression promotes the expansion of adult blood progenitors and blocks B cell development |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Here we use a microarray approach to define at the molecular level the consequences of SOX7-mediated effect on B lymphopoiesis and progenitor proliferation. Transcriptome profiling analysis was performed on two subpopulations expressing low and high level of SOX7::GFP.
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| |
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| Overall design |
Bone marrow cells extracted from iSox7 transgenic mice were treated with and without dox in duplicate
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| |
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| Contributor(s) |
Cuvertino S, Kouskoff V |
| Citation(s) |
27411892 |
| |
| Submission date |
Feb 03, 2015 |
| Last update date |
Mar 03, 2017 |
| Contact name |
Valerie Kouskoff |
| E-mail(s) |
valerie.kouskoff@cruk.manchester.ac.uk
|
| Organization name |
Cancer Research UK Manchester Institute
|
| Lab |
Stem cell hematopoisis
|
| Street address |
Wilmslow Road
|
| City |
Manchester |
| ZIP/Postal code |
M20 4BX |
| Country |
United Kingdom |
| |
|
| Platforms (1) |
| GPL6193 |
[MoEx-1_0-st] Affymetrix Mouse Exon 1.0 ST Array [probe set (exon) version] |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA274358 |
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