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| Status |
Public on May 10, 2016 |
| Title |
Aflatoxin B1 exposure induces epigenetic mechanisms in primary human hepatocytes revealing novel biological processes associated with hepatocellular carcinoma (miRNA) |
| Organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
|
| Summary |
The study investigated differential gene expression, microRNA expression and DNA methylation changes in a pool of primary human hepatocyte RNA and DNA following 5 days of repetitive exposure to a low or moderate dose of aflatoxin B1 or DMSO. Three biological replicates per compound/solvent.
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| |
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| Overall design |
In total 9 arrays. The PHH_5D_MD_control and PHH_LD_5D_control Samples are the same Samples just processed differently. The raw data files for these Samples are on the Series record.
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| |
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| Contributor(s) |
Rieswijk L |
| Citation(s) |
27153756 |
| |
| Submission date |
Mar 17, 2015 |
| Last update date |
May 12, 2016 |
| Contact name |
Linda Rieswijk |
| E-mail(s) |
linda.rieswijk@maastrichtuniversity.nl
|
| Organization name |
Maastricht University
|
| Department |
Toxicogenomics
|
| Street address |
Universiteitssingel 50
|
| City |
Maastricht |
| ZIP/Postal code |
6229 ER |
| Country |
Netherlands |
| |
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| Platforms (1) |
| GPL18402 |
Agilent-046064 Unrestricted_Human_miRNA_V19.0_Microarray (miRNA ID version) |
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| Samples (12)
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| This SubSeries is part of SuperSeries: |
| GSE67078 |
Aflatoxin B1 exposure induces epigenetic mechanisms in primary human hepatocytes revealing novel biological processes associated with hepatocellular carcinoma |
|
| Relations |
| BioProject |
PRJNA278735 |
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