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Series GSE6715 Query DataSets for GSE6715
Status Public on Feb 15, 2007
Title DNA methylation, RNA Pol2 binding and H3-K4me2 of human promoters in WI38 primary fibroblasts and sperm cells
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by genome tiling array
Methylation profiling by genome tiling array
Summary To gain insights into the function of DNA methylation at cis-regulatory regions and its impact on gene expression, we measured methylation, RNA polymerase II and histone modifications at 24.000 promoters in primary human soma and germline cells.
Keywords: DNA methylation, MeDIP
 
Overall design The chosen array from NIMBLEGEN (HG17_min_promoter array) represents 24134 putative human promoters, each covered by 15 oligonucleotides spanning 1.3 kb upstream and 0.2 kb downstream of the transcription start site. All experiments have been repeated two or three times, including one dye-swop.
 
Contributor(s) Weber M, Stadler MB, Rebhan M, Schubeler D
Citation(s) 17334365
Submission date Jan 11, 2007
Last update date Mar 16, 2012
Contact name Michaël Weber
E-mail(s) michael.weber@fmi.ch
Organization name Friedrich Miescher Institute
Department Epigenetics
Lab Dirk Schübeler
Street address Maulbeerstrasse 66
City Basel
ZIP/Postal code CH 4058
Country Switzerland
 
Platforms (1)
GPL3497 NimbleGen hg17 Human 1.5 Kb MinPromoter array
Samples (11)
GSM154827 WI38 cells_MeDIP_Replicate1
GSM154828 WI38 cells_MeDIP_Replicate2
GSM154830 human sperm cells_MeDIP_Replicate1
Relations
BioProject PRJNA99041

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary data files not provided

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