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Status |
Public on Sep 01, 2015 |
Title |
Transcriptomic signatures of Auger electron radioimmunotherapy using nuclear targeting 111In-trastuzumab for potential combination therapies |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
The aim of this study was to identify targetable molecular signatures for enhancing the cytotoxic effects of In-111-trastuzumab-NLS using microarray technology.
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Overall design |
Changes in gene expression in SKBR3 cells untreated or treated with unlabeled or In-111-labeled antibodies for 7 days were measured. Three independent experiments in each condition were performed.
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Contributor(s) |
Li H, Morokoshi Y, Daino K, Furukawa T, Kamada T, Saga T, Hasegawa S |
Citation(s) |
26447839 |
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Submission date |
Mar 24, 2015 |
Last update date |
Jan 09, 2018 |
Contact name |
Kazuhiro DAINO |
E-mail(s) |
daino.kazuhiro@qst.go.jp
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Organization name |
National Institutes for Quantum and Radiological Science and Technology
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Street address |
4-9-1 Anagawa, Inage-ku
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City |
Chiba |
ZIP/Postal code |
263-8555 |
Country |
Japan |
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Platforms (1) |
GPL17077 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version) |
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Samples (15)
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Relations |
BioProject |
PRJNA279237 |