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| Status |
Public on Mar 31, 2015 |
| Title |
Gene expression analysis in the adult carotid body stem cell niche |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
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| Summary |
The carotid body (CB) is a peripheral chemoreceptor organ that suffers a profound angiogenic and neurogenic process in response to hypoxemia, to contribute to physiological adaptation of the organism.
We have previously described a subpopulation of neural crest-derived stem cells residing in the organ. These cells are responsible for hypoxia-induced neurogenesis. Little is known about the molecular mechanisms underlying this neurogenic process.
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| Overall design |
We have used neuronal cell-enriched neurosphere (NS) cultures vs. undifferentiated cell-enriched NS to study molecular pathways involved in the biology of these CB different cell types.
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| Contributor(s) |
Pardal R, Platero-Luengo A |
| Citation missing |
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| |
| Submission date |
Mar 30, 2015 |
| Last update date |
Mar 31, 2015 |
| Contact name |
Ricardo Pardal |
| E-mail(s) |
rpardal@us.es
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| Organization name |
University of Seville
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| Department |
Medical Physiology and Biophysics
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| Lab |
Physiopathology of neural stem cells
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| Street address |
Avda. Manuel Siurot, s/n.
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| City |
Seville |
| ZIP/Postal code |
41013 |
| Country |
Spain |
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| Platforms (1) |
| GPL6247 |
[RaGene-1_0-st] Affymetrix Rat Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA279876 |
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