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Status |
Public on May 12, 2016 |
Title |
MLL1 and MLL fusion proteins play distinct roles in regulating MLLleukemic transcription program [ChIP-Seq] |
Organism |
Mus musculus |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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Summary |
This study describes the epigenetic profiling change of 1.) Mll1, WDR5 and H3K4me2 in mouse MAF9 leukemia cells treated with or without MM401; 2.) WDR5 and H3K4me2 epigenetic profiling in MLL1 flox/flox, ER-Cre+/- cells with knocking out MLL1 by 4OHT or not.
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Overall design |
ChIP-Seq profile of Mll1, WDR5 and H3K4me2 were generated in MAF9 cells or MLL1 flox/flox, ER-cre+/- cells. A sequence profile of genomic DNA (Input) is also included.
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Contributor(s) |
Dou Y, Xu J |
Citation(s) |
27462455 |
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Submission date |
May 13, 2015 |
Last update date |
May 15, 2019 |
Contact name |
Yali Dou |
E-mail(s) |
yalid@med.umich.edu
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Phone |
(734) 615-1315
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Organization name |
University of Michigan
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Department |
Pathology Department
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Lab |
5215 Medical Science Building I
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Street address |
1301 Catherine Street
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City |
Ann Arbor |
State/province |
MI |
ZIP/Postal code |
48109 |
Country |
USA |
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Platforms (1) |
GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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Samples (14)
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This SubSeries is part of SuperSeries: |
GSE68823 |
MLL1 and MLL fusion proteins play distinct roles in regulating MLLleukemic transcription program |
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Relations |
BioProject |
PRJNA283891 |
SRA |
SRP058280 |