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| Status |
Public on May 01, 2016 |
| Title |
Aberrantly expressed long noncoding RNAs in the eutopic endometrium of women with adenomyosis |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
Non-coding RNA profiling by array
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| Summary |
Objective: To identify differentially expressed long noncoding RNA in the eutopic endometrium tissue of adenomyosis on a genome-wide scale. Patient(s): Seventeen women with adenomyosis and fifteen patients without adenomyosis or endometriosis receiving surgical treatment. Intervention(s): Total RNAs containing long nocoding RNAs was extracted from endometrial tissue obtained during surgery. Main Outcome Measure(s): Differentially expressed lncRNAs and mRNAs were detected by human lncRNA microarray. Result(s): We identified 165 lncRNAs and 612 mRNAs abnormally expressed (P<0.05) in the eutopic endometrium of adenomyosis. Conclusion(s): This study showed for the first time that the lncRNA expression profile was altered in women with adenomyosis.
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| Overall design |
Total 8 samples was analyzed, including 4 samples in the experiment group and 4 in the control group.
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| Contributor(s) |
Jiang FJ, Sun JA |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
May 14, 2015 |
| Last update date |
Oct 29, 2018 |
| Contact name |
fa jian jiang |
| E-mail(s) |
670561033@qq.com
|
| Phone |
18600906923
|
| Organization name |
Peking Union Medical College Hospital
|
| Department |
Obstetrics and Gynecology
|
| Street address |
Dongcheng District, Shuaifuyuan NO.1
|
| City |
Beijing |
| ZIP/Postal code |
100730 |
| Country |
China |
| |
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| Platforms (1) |
| GPL17586 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
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| Samples (8)
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| GSM1684739 |
endometrium in the proliferative phase_A1 |
| GSM1684740 |
endometrium in the secretory phase_A2 |
| GSM1684741 |
endometrium in the secretory phase_A3 |
| GSM1684742 |
endometrium in the proliferative phase_A4 |
| GSM1684743 |
endometrium in the secretory phase_C1 |
| GSM1684744 |
endometrium in the proliferative phase_C2 |
| GSM1684745 |
endometrium in the proliferative phase_C3 |
| GSM1684746 |
endometrium in the secretory phase_C4 |
|
| Relations |
| BioProject |
PRJNA283948 |
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