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| Status |
Public on Jul 11, 2015 |
| Title |
In-vivo Gene Signatures of Mycobacterium tuberculosis In C3HeB/FeJ Mice |
| Platform organisms |
Mycobacterium tuberculosis CDC1551; Mycobacterium tuberculosis H37Rv |
| Sample organism |
Mycobacterium tuberculosis H37Rv |
| Experiment type |
Expression profiling by array
|
| Summary |
In-vivo Gene Signatures of Mycobacterium tuberculosis In C3HeB/FeJ Mice
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| Overall design |
In this experiment we have compared Mtb transcriptomics in-vivo, using samples derived from chronically infected C3HeB/FeJ mice, which produce human like caseating lesions, unlike other murine species, to Mtb cultured in-vitro. Similarly, the genome-wide expression of MtbdeldosR, MtbdeldosS and MtbdeldosT mutants is also compared between lungs from C3HeB/FeJ mice and in-vitro culturing.
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| |
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| Contributor(s) |
Kaushal D, Gautam US |
| Citation(s) |
26270051 |
| |
| Submission date |
Jul 10, 2015 |
| Last update date |
Oct 19, 2015 |
| Contact name |
Deepak Kaushal |
| E-mail(s) |
dkaushal@tulane.edu
|
| Organization name |
Tulane National Primate Research Center
|
| Department |
Bacteriology
|
| Lab |
Kaushal
|
| Street address |
18703 Three Rivers Rd
|
| City |
Covington |
| State/province |
LA |
| ZIP/Postal code |
38105 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL18320 |
MYcroarray Mycobacterium tuberculosis str. H37Rv and str. CDC1551 array |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA289506 |
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