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| Status |
Public on Oct 31, 2015 |
| Title |
Global Gene Expression Profiles of Fibroblasts from the Lungs of Patients with Idiopathic Pulmonary Fibrosis: The Role of CCL8 |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Analysis of Idiopathic pulmonary fibrosis (IPF) at gene expression level. The hypothesis tested in the present study was that Epigenetic mechanisms are likely to be associated with pathogenesis in IPF. To determine the DNA methylation change, and their effects on gene expression, we compared microarray data of DNA methylation and RNA expression. Results provide that among the genes whose DNA methylation status and RNA expression were both significantly altered between IPF-rapid and normal controls.
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| |
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| Overall design |
Total RNA obtained from Idiopathic pulmonary fibrosis samples.
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| |
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| Contributor(s) |
Lee J, Park C |
| Citation(s) |
28057004 |
| |
| Submission date |
Jul 27, 2015 |
| Last update date |
Aug 13, 2018 |
| Contact name |
Hyun Sub Cheong |
| E-mail(s) |
chhs@snp-genetics.com
|
| Phone |
82-2-3273-1677
|
| Organization name |
SNP Genetics, Inc.
|
| Department |
Genetic Epidemiology
|
| Street address |
#1007, Teihard Hall, Sogang Univ. Baekbum-ro 35, Mapo-gu
|
| City |
Seoul |
| ZIP/Postal code |
121-742 |
| Country |
South Korea |
| |
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| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA291029 |
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