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Status |
Public on Apr 29, 2016 |
Title |
Human periheral blood-derived monocytes and unstimulated as well as IL-4-stimulated differentiating macrophages |
Platform organism |
synthetic construct |
Sample organism |
Homo sapiens |
Experiment type |
Non-coding RNA profiling by array
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Summary |
CD14+ monocytes were separated from human peripheral blood and exposed to IL-4 for 12 or 72 hours then subjected to microarray analysis We used Affymetrix miRNA1.0 microarray to obtain global miRNA expression data of human monocytes, unstimulated and IL-4-stimulated differentiating macrophages.
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Overall design |
CD14+ monocytes were separated from human peripheral blood and exposed to IL-4 for 12 or 72 hours. The global miRNA expression patterns of human monocytes, unstimulated and IL-4-stimulated differentiating macrophages were analyzed on Affymetrix microarrays.
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Contributor(s) |
Czimmerer Z, Varga T, Kiss M, Vázquez CO, Doan-Xuan QM, Rückerl D, Tattikota SG, Nagy ZS, Daniel B, Poliska S, Horvath A, Nagy G, Varallyay E, Poy MN, Allen JE, Bacso Z, Abreu-Goodger C, Nagy L |
Citation(s) |
27245778 |
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Submission date |
Aug 03, 2015 |
Last update date |
May 02, 2017 |
Contact name |
Szilard Poliska |
E-mail(s) |
poliska@dote.hu
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Phone |
+3652416432
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Organization name |
University of Debrecen
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Department |
Biochemistry and Molecular Biology
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Lab |
Nuclear Hormone Receptor Research Laboratory
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Street address |
Egyetem ter 1.
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City |
Debrecen |
ZIP/Postal code |
H-4012 |
Country |
Hungary |
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Platforms (1) |
GPL8786 |
[miRNA-1] Affymetrix Multispecies miRNA-1 Array |
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Samples (15)
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GSM1842191 |
control_72 hours, Donor 1 |
GSM1842192 |
IL-4_72 hours, Donor 1 |
GSM1842193 |
monocytes, Donor 2 |
GSM1842194 |
control_12 hours, Donor 2 |
GSM1842195 |
IL-4_12 hours, Donor 2 |
GSM1842196 |
control_72 hours, Donor 2 |
GSM1842197 |
IL-4_72 hours, Donor 2 |
GSM1842198 |
monocytes, Donor 3 |
GSM1842199 |
control_12 hours, Donor 3 |
GSM1842200 |
IL-4_12 hours, Donor 3 |
GSM1842201 |
control_72 hours, Donor 3 |
GSM1842202 |
IL-4_72 hours, Donor 3 |
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This SubSeries is part of SuperSeries: |
GSE71644 |
The IL4-STAT6 signaling axis establishes a conserved microRNA signature in human and mouse macrophages regulating cell survival via miR-342-3p |
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Relations |
BioProject |
PRJNA291696 |
Supplementary file |
Size |
Download |
File type/resource |
GSE71641_RAW.tar |
2.2 Mb |
(http)(custom) |
TAR (of CEL) |
GSE71641_miRNAQCtool_Summarization.csv.gz |
1.2 Mb |
(ftp)(http) |
CSV |
Processed data included within Sample table |
Processed data provided as supplementary file |
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