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| Status |
Public on Sep 06, 2017 |
| Title |
Next Generation Sequencing Transcriptomes of breast cancer |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We performed high throughput transcriptome of breast cancer and normal tissues, identifying lincRNA associated molecular subtype with powerful capacity to distinct breast cancer population and predict prognosis. We also identified subtype-specific lincRNAs that may be a useful complement to intrinsic molecular subtype classification when divergence emerges among pathologists.Paired-end transcriptome sequencing were carried out on a cohort of 33 breast tissues from 11 groups including five breast cancer subtypes including luminal A (LA), luminal B (HER2 negative)(LB, HER2-), luminal B (HER2 positive) (LB, HER2+), HER2 and tripple negative breast cancer (TNB), adjacent noncancerous breast tissue (ANT, three samples for each subtype) and the complete normal breast tissues (three samples)
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| |
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| Overall design |
Examination of transcriptomes in 15 breast cancer and 18 normal tissues.
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| |
|
| Contributor(s) |
Pang D, Xu S |
| Citation(s) |
28738804, 30764831, 30999914, 31395854, 31801944 |
| |
| Submission date |
Aug 03, 2015 |
| Last update date |
Dec 09, 2019 |
| Contact name |
shipeng shang |
| E-mail(s) |
bio_shangsp@163.com
|
| Organization name |
Department of Breast Surgery, Harbin Medical University Cancer Hospital
|
| Street address |
XueFu Road 194, NanGang District
|
| City |
Harbin |
| ZIP/Postal code |
150081 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL9115 |
Illumina Genome Analyzer II (Homo sapiens) |
|
| Samples (33)
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| Relations |
| BioProject |
PRJNA292118 |
| SRA |
SRP062132 |
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