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Series GSE72486 Query DataSets for GSE72486
Status Public on Dec 21, 2016
Title A transcription factor pulse can prime chromatin for heritable transcriptional memory [ChIPseq]
Organism Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary To investigate the epigenetic control of long-term transcriptionnal memory (LTTM) we used a trans-differentiation system where Bcell are reprogramed into macrophages upon induction of the transcription factor Cebpa. We performed ChIPseq in untreated Bcells, after 12h of Cebpa induction and after 6days of “wash” of Cebpa, to see if any proteins/histone marks are retained.
 
Overall design Genome binding/occupancy of transcription factor Pu1 and histones (H3K4me1/2/3 and H3K27me3) by ChIPseq in uninduced Bcell (Control), after induction Cebpa for 6h (Pulse) and after 6 days of wash (Chase).
 
Contributor(s) Badeaux A, Collombet S, Graf T, Thieffry D, Shi Y
Citation(s) 27920256
Submission date Aug 28, 2015
Last update date May 15, 2019
Contact name samuel Collombet
E-mail(s) samuelcollombet@gmail.com
Organization name Ecole Normale Superieure
Department Biology
Lab Thieffry
Street address 46 rue d'Ulm
City Paris
ZIP/Postal code 75005
Country France
 
Platforms (1)
GPL13112 Illumina HiSeq 2000 (Mus musculus)
Samples (17)
GSM1863152 Chase_H3K4me1
GSM1863153 Chase_H3K4me2
GSM1863154 Chase_H3K4me3
This SubSeries is part of SuperSeries:
GSE72488 A transcription factor pulse can prime chromatin for heritable transcriptional memory
Relations
BioProject PRJNA294146
SRA SRP062944

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE72486_RAW.tar 2.4 Gb (http)(custom) TAR (of BW)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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