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| Status |
Public on Mar 30, 2018 |
| Title |
RNA expression in MDA-MB-231 cells transfected with scramble, LSD1 or HDAC5 shRNA (HG-U133A_2) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
We performed gene expression microarray to examine the potential effect that depletion of HDAC5 (an important HDAC isozyme) or LSD1 (an FAD-dependent histone lysine demethylase) has on the triple-negative breast cancer transcriptome.
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| Overall design |
Twelve samples were subject to microarray anaylsis: 3 biological replicates were treated with 1) scramble shRNA, 2) HDAC5 shRNA, 3) scramble shRNA, or 4) LSD1 shRNA.
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| Contributor(s) |
Vasilatos SN, Cao C, Huang Y |
| Citation(s) |
29633255 |
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| Submission date |
Sep 03, 2015 |
| Last update date |
Dec 06, 2018 |
| Contact name |
Yi Huang |
| Organization name |
University of Pittsburgh Cancer Institute
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| Department |
Pharmacology & Chemical Biology
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| Lab |
MWRI, B430I/J
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| Street address |
204 Craft Ave
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| City |
Pittsburgh |
| State/province |
Pennsylvania |
| ZIP/Postal code |
15213 |
| Country |
USA |
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| Platforms (1) |
| GPL571 |
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array |
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| Samples (12)
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| GSM1868467 |
MM231 cells tfxn scramble shRNA, biological rep1 |
| GSM1868468 |
MM231 cells tfxn scramble shRNA, biological rep2 |
| GSM1868469 |
MM231 cells tfxn scramble shRNA, biological rep3 |
| GSM1868470 |
MM231 cells tfxn HDAC5 shRNA, biological rep1 |
| GSM1868471 |
MM231 cells tfxn HDAC5 shRNA, biological rep2 |
| GSM1868472 |
MM231 cells tfxn HDAC5 shRNA, biological rep3 |
| GSM2911378 |
MM231 cells tfxn scramble shRNA (LSD1), biological repA |
| GSM2911379 |
MM231 cells tfxn scramble shRNA (LSD1), biological repB |
| GSM2911380 |
MM231 cells tfxn scramble shRNA (LSD1), biological repC |
| GSM2911381 |
MM231 cells tfxn LSD1 shRNA, biological rep1 |
| GSM2911382 |
MM231 cells tfxn LSD1 shRNA, biological rep2 |
| GSM2911383 |
MM231 cells tfxn LSD1 shRNA, biological rep3 |
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| Relations |
| BioProject |
PRJNA294669 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE72687_RAW.tar |
23.7 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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