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Series GSE73894 Query DataSets for GSE73894
Status Public on Jul 07, 2017
Title Genome-wide DNA methylation analysis of psoriatic and normal skin tissues
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary Genome wide DNA methylation profiling of psoriatic (PP), paired uninvolved psoriatic (PN) and normal skin tissues (NN). The Illumina Infinium 450k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 485,000 CpGs in 135 PP, 41PN and 62 NN tissues which were obtained from those who underwent skin biospsies. We not only revealed a genome-wide methylation level pattern for psoriasis, but also identified a strong association between the skin-specific DNAm of 9 DMS and psoriasis.
 
Overall design Bisulphite converted DNA from the 217 samples were hybridised to the Illumina Infinium 450k Human Methylation Beadchip v1.2
 
Contributor(s) Zhou F, Zhang X
Citation(s) 26743604, 30587242
Submission date Oct 09, 2015
Last update date Mar 22, 2019
Contact name Fusheng Zhou
E-mail(s) biozhoufs@163.com
Organization name Anhui Medical University
Street address No 96 Meishan Road, Hefei, China
City Hefei
ZIP/Postal code 230032
Country China
 
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (219)
GSM1905080 genomic DNA from uninvolved psoriatic skin sample 161
GSM1905081 genomic DNA from uninvolved psoriatic skin sample 163
GSM1905082 genomic DNA from uninvolved psoriatic skin sample 164
Relations
BioProject PRJNA298351

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE73894_Matrix_signal_intensities.txt.gz 550.2 Mb (ftp)(http) TXT
GSE73894_RAW.tar 183.1 Mb (http)(custom) TAR
Processed data included within Sample table
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