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Series GSE74757 Query DataSets for GSE74757
Status Public on Nov 06, 2015
Title ZFP57 recognizes multiple and closely spaced sequence motif variants to maintain repressive epigenetic marks in mouse embryonic stem cells
Organism Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary In mouse embryonic stem cells SNPs disrupting closely-spaced hexanucleotide motifs are associated with lack of ZFP57 binding and H3K9me3 enrichment.
 
Overall design Examination of ZFP57-KAP1 allele-specific binding in two lines of mouse embryonic stem cells JB1 and BJ1 generated from F1 hybrids derived from JF1 x B6 and B6 x JF1 crosses respectively.
Web link http://genome.ucsc.edu/cgi-bin/hgTracks?hgS_doOtherUser=submit&hgS_otherUserName=bioinformatico&hgS_otherUserSessionName=Anvar_et_al_2015_NAR
 
Contributor(s) Anvar Z, Cammisa M, Riso V, Baglivo I, Kukreja H, Sparago A, Girardot M, Lad S, De Feis I, Cerrato F, Angelini C, Feil R, Pedone PV, Grimaldi G, Riccio A
Citation(s) 26481358
Submission date Nov 06, 2015
Last update date May 15, 2019
Contact name Marco Cammisa
E-mail(s) cammisamarco.py@gmail.com
Organization name Institute of Genetics and Biophysics "A. Buzzati Traverso" (IGB-ABT)
Street address Via Castellino Pietro, 111
City Naples
State/province Naples
ZIP/Postal code 80131
Country Italy
 
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (6)
GSM1931782 BJ1 Input
GSM1931783 BJ1 ZFP57
GSM1931784 BJ1 KAP1
Relations
BioProject PRJNA301413
SRA SRP065888

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE74757_RAW.tar 1.7 Gb (http)(custom) TAR (of BED, BEDGRAPH)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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