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| Status |
Public on Mar 31, 2017 |
| Title |
Crosstalk between Streptococcus mutans and Aggregatibacter actinomycetemcomitans in dual-species biofilms. |
| Organisms |
Aggregatibacter actinomycetemcomitans; Streptococcus mutans |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
We performed comparative analysis of transcriptomes of S. mutans in single biofilms and in mixed-biofilms with A. actinomycetemcomitans. We also compared the transcriptomic profiles of A. actinomycetemcomitans in single biofilms and A. actinomycetemcomitans in mixed biofilms with S. mutans. Finally we looked at the changes in gene expression in both organisms in time.
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| Overall design |
RNAseq of single species biofilms (S. mutans, A.act.) - 8 and 24 h, dual-species biofilms (S.mutans with A.act.) - 4, 6, 8,10, 12, and 24 h. All in duplicate. Using Illumina HiSeq.
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| Contributor(s) |
Szafranski SP, Tomasch J, Deng Z, Jarek M, Bhuju S, Rohde M, Sztajer H, Wagner-Doebler I |
| Citation(s) |
28320314 |
| |
| Submission date |
Nov 15, 2015 |
| Last update date |
May 15, 2019 |
| Contact name |
Szymon Piotr Szafranski |
| Organization name |
Helmholtz Centre for Infection Research
|
| Department |
Research Group Microbial Communication
|
| Street address |
Inhoffenstr. 7
|
| City |
Braunschweig |
| ZIP/Postal code |
D-38124 |
| Country |
Germany |
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| Platforms (3) |
| GPL21140 |
Illumina HiSeq 2500 (Streptococcus mutans) |
| GPL21141 |
Illumina HiSeq 2500 (Aggregatibacter actinomycetemcomitans) |
| GPL21142 |
Illumina HiSeq 2500 (Aggregatibacter actinomycetemcomitans; Streptococcus mutans) |
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| Samples (20)
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| Relations |
| BioProject |
PRJNA302227 |
| SRA |
SRP066217 |
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