|
| Status |
Public on Apr 08, 2016 |
| Title |
Modulation of tissue repair by regeneration enhancer elements. |
| Organism |
Danio rerio |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We compared transcriptional and chromatin profiles of regenerating zebrafish hearts following genetic ablation with profiles from uninjured zebrafish hearts.
|
| |
|
| Overall design |
Examination of whole heart transcriptional profiles from ablated hearts (2 pools of 10 hearts) and uninjured hearts (2 pools of 10 hearts).
Examination of differential H3K27Ac marks following genetic ablation of cardiomyocytes (regenerating hearts) and uninjured hearts.
|
| |
|
| Contributor(s) |
Karra R, Poss K |
| Citation(s) |
27049946 |
| |
| Submission date |
Dec 10, 2015 |
| Last update date |
May 15, 2019 |
| Contact name |
Ravi Karra |
| E-mail(s) |
ravi.karra@duke.edu
|
| Organization name |
Duke
|
| Department |
Cell Biology
|
| Lab |
Poss
|
| Street address |
464 Nanaline Duke, 307 Research Drive
|
| City |
Durham |
| State/province |
NC |
| ZIP/Postal code |
27710 |
| Country |
USA |
| |
|
| Platforms (2) |
| GPL9319 |
Illumina Genome Analyzer II (Danio rerio) |
| GPL14875 |
Illumina HiSeq 2000 (Danio rerio) |
|
| Samples (8)
|
| GSM1969523 |
ZF_Uninjured_Hearts_2 (PG-2) |
| GSM2152256 |
Regenerating zebrafish hearts H3K27Ac ChIP-Seq, 1 |
| GSM2152257 |
Regenerating zebrafish hearts H3K27Ac ChIP-Seq, 2 |
| GSM2152258 |
Uninjured zebrafish hearts H3K27Ac ChIP-Seq, 1 |
| GSM2152259 |
Uninjured zebrafish hearts H3K27Ac ChIP-Seq, 2 |
|
| Relations |
| BioProject |
PRJNA305621 |
| SRA |
SRP067229 |
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