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Series GSE7670 Query DataSets for GSE7670
Status Public on Aug 30, 2007
Title Expression data from Lung cancer
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Detection, treatment, and prediction of outcome for lung cancer patients increasingly depend on a molecular understanding of tumor development and sensitivity of lung cancer to therapeutic drugs. The application of genomic technologies, such as microarray, is widely used to monitor global gene expression and has built up invaluable information and knowledge, which is essential to the discovery of new insights into the mechanisms common to cancer cells, resulting in the identification of unique, identifiable signatures and specific characteristics. It is likely that application of microarray may revolutionize many aspects of lung cancer being diagnosed, classified, and treated in the near future. We used microarrays to detail the global gene expression patterns of lung cancer.
Keywords: Disease state analysis
 
Overall design Adjacent normal-tumor matched lung cancer samples were selected at early and late stages for RNA extraction and hybridization on Affymetrix microarrays. A total of 66 samples were used for microarray analysis, including pairwise samples from 27 patients, who underwent surgery for lung cancer at the Taipei Veterans General Hospital, two tissue mixtures from the Taichung Veterans General Hospital (one was adjacent normal lung mixtures and the other was lung adenocarcinoma mixtures), two commercial human normal lung tissues (Clontech (Catalog No. 636524) and Stratagene (Catalog No. 735020)), one immortalized, nontumorigenic human bronchial epithelial cell line (NL-20 (ATCC® No. CRL-2503)), and 7 lung cancer cell lines (A-549 (ATCC® No. CCL-185), NCI-H1299 (ATCC® No. CRL-5803), NCI-H661 (ATCC® No. HTB-183), CL1-0, CL1-1, CL1-5 and CL1-5-F4.
 
Contributor(s) Su L, Huang CF, Wu Y
Citation(s) 17540040, 19337377
Submission date Apr 30, 2007
Last update date Sep 26, 2019
Contact name Li-Jen Su
E-mail(s) ljsu@vghtpe.gov.tw
Organization name Taipei Veterans General Hospital
Department Department of Surgery
Street address No. 201, Sec. 2, Shih-Pai Road
City Taipei
ZIP/Postal code 112
Country Taiwan
 
Platforms (1)
GPL96 [HG-U133A] Affymetrix Human Genome U133A Array
Samples (66)
GSM185811 1N: Adjacent normal part of adenocarcinoma
GSM185812 1T: Tumor part of adenocarcinoma
GSM185813 2N: Adjacent normal part of adenocarcinoma
Relations
BioProject PRJNA99719

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Supplementary file Size Download File type/resource
GSE7670_RAW.tar 217.9 Mb (http)(custom) TAR (of CEL, EXP)
Processed data included within Sample table
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