|
| Status |
Public on Feb 24, 2016 |
| Title |
Protoarray based identificatoin of dysregulated proteins in metastatic osteosarcoma |
| Organism |
Homo sapiens |
| Experiment type |
Protein profiling by protein array
|
| Summary |
Our results successfully showed through profiling of 8268 proteins that five autoantibodies in the metastatic group showed significantly higher intensities than non-metastatic and control groups
Healthy or non-cancerous pediatric patients were pooled into a control group; Human ProtoArray that contains total 19200 protein spots of which 1326 are control spots and 8,268 are unique human proteins
|
| |
|
| Overall design |
In the study presented here we pooled plasma samples from Osteosarcoma patients who developed metastasis and localized disease within the first year of follow-up into a metastatic group and a non-metastatic group respectively and were used to acquire expression profiles of a total of 8268 proteins leading to successful identification of 5 proteins.
|
| |
|
| Contributor(s) |
Man T, Nakka M |
| Citation(s) |
27197201 |
| |
| Submission date |
Feb 23, 2016 |
| Last update date |
May 25, 2016 |
| Contact name |
Tsz-Kwong Man |
| Organization name |
Baylor College of Medicine
|
| Department |
Pediatrics
|
| Lab |
Cancer Center
|
| Street address |
1102 Bates,
|
| City |
Houston |
| State/province |
TX |
| ZIP/Postal code |
77030 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL21502 |
Invitrogen ProtoArray v4 human protein microarray lot HA20085 [Array_ID version] |
|
| Samples (9)
|
|
| Relations |
| BioProject |
PRJNA312894 |
Less...
More...