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Series GSE79232 Query DataSets for GSE79232
Status Public on Mar 16, 2016
Title Gene expression profiling in humna HCC, lung, and pancreas cell lines.
Organism Homo sapiens
Experiment type Expression profiling by array
Summary To investigate the role for LSD1 in solid cancer cell growth, we depleted LSD1 with siRNA in 50 different cancer cell lines derived from various tissues. By the degree to the cell growth defect mediated by LSD1 knock down, we stratified the cell lines into three groups. Then, to determine differential gene expressions related to the LSD1-dependent cell growth, we performed gene expression microarray analyses of the most and the least LSD1-dependent cell lines.
Overall design Gene expression analysis of 21 cell lines under normal cell culture condition.
Determined the gene expression profile of the most and the least LSD1-dependent group by Gene Set Enrichment Analysis (GSEA), and decided to identify the biological pathways correlated with the LSD1 dependence of cell growth.
Contributor(s) Yang S, Jang YJ, Kim J, Yeom YI
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Submission date Mar 15, 2016
Last update date Aug 09, 2016
Contact name Yang Suk-Jin
Organization name KRIBB (Korea Research Institute of Bioscience and Biotechnology)
Street address 125 Gwahak-ro, Yuseong-gu
City Daejeon
ZIP/Postal code 34141
Country South Korea
Platforms (2)
GPL10904 Illumina HumanHT-12 V4.0 expression beadchip (gene symbol)
GPL16700 Illumina HumanHT-12 V3.0 expression beadchip [gene symbol; HumanHT-12_V3_0_R3_11283641_A]
Samples (21)
GSM2088511 HLF
GSM2088512 JHH-4
GSM2088513 JHH-6
BioProject PRJNA315214

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE79232_RAW.tar 13.1 Mb (http)(custom) TAR
GSE79232_non_normalized_GSM2088511-20.txt.gz 1.8 Mb (ftp)(http) TXT
GSE79232_non_normalized_GSM2088521-30.txt.gz 1.7 Mb (ftp)(http) TXT
GSE79232_non_normalized_GSM2264694.txt.gz 385.1 Kb (ftp)(http) TXT
Processed data included within Sample table

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