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| Status |
Public on Apr 03, 2016 |
| Title |
Expression data from HHG affected and unaffected Vulpes vulpes gingival samples |
| Platform organism |
Canis lupus familiaris |
| Sample organism |
Vulpes vulpes |
| Experiment type |
Expression profiling by array
|
| Summary |
Hereditary hyperplastic gingivitis (HHG) is a progressive growth of gingival tissues in foxes resulting in dental encapsulation. It is an autosomal recessive condition displaying a sex-biased penetrance, with an association with superior fur quality. The goal of this study was to explore potential molecular or cellular mechanisms underlying HHG by analysis of global gene expression patterns from Affymetrix Canine 2.0 microarrays cross-referenced.
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| Overall design |
HHG affected and unaffected Vulpes vulpes gingival samples were collected either during pelting season or in the late spring after whelping season. Diagnosis of HHG was made based on early markers of the disease where red, raised, granular gingival tissue was present at the dental margins on the crowns of the teeth. RNA was extracted and hybridization on Affymetrix Canine 2 microarray.
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| Contributor(s) |
Clark J, Marshall HD |
| Citation(s) |
25469536 |
| |
| Submission date |
Apr 02, 2016 |
| Last update date |
Oct 10, 2016 |
| Contact name |
Jo-Anna Barbara Joyce Clark |
| E-mail(s) |
j.clark@mun.ca
|
| Organization name |
Memorial University
|
| Department |
Biology
|
| Lab |
Marshall
|
| Street address |
Elizabeth Avenue
|
| City |
St. John's |
| State/province |
Newfoundland |
| ZIP/Postal code |
A1B3X9 |
| Country |
Canada |
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| Platforms (1) |
| GPL3738 |
[Canine_2] Affymetrix Canine Genome 2.0 Array |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA317237 |
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