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| Status |
Public on Sep 01, 2016 |
| Title |
Gene Expression Analysis Indicates Divergent Mechanisms in DEN-Induced Carcinogenesis in Wild Type and Bid-Deficient Livers |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
The aim of this study was to better understand the Bid-regulated events during hepatic carcinogenesis.
The information from this set of data indicates that wild type and bid-deficient livers express different sets of genes after diethylnitrosamine (DEN) treatment.
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| Overall design |
We performed gene expression analysis in wild type and bid-deficient mice treated with DEN for 4-6 months and for 10-12 months. The expression was compared among the different groups to understand the effect of deletion of Bid on gene epxression at the early (4-6 month) and the later (10-12 months) stage.
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| Contributor(s) |
Yin X, Yu C |
| Citation(s) |
27196317 |
| Submission date |
Apr 20, 2016 |
| Last update date |
Feb 18, 2018 |
| Contact name |
Xiaoming Yin |
| Organization name |
Indiana University School of Medicine
|
| Department |
Department of Pathology and Laboratory Medicine
|
| Lab |
Indiana University Health Pathology Laboratory
|
| Street address |
350 West 11th street
|
| City |
Indianapolis |
| State/province |
Indiana |
| ZIP/Postal code |
46202 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL81 |
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array |
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| Samples (30)
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| Relations |
| BioProject |
PRJNA319040 |
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