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Series GSE80775 Query DataSets for GSE80775
Status Public on May 02, 2018
Title Characterization of a spontaneous model of inflammation-derived liver cancer [ChIP-seq]
Organism Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary Induction of a protective response to oxidative stress, both from a transcriptional and from a genetic viewpoint, confers a selective advantage for cells exposed to an inflammatory environment, paving the way to neoplastic transformation
 
Overall design Chromatin immuno-precipitations of acetylated lysine 27 of H3 followed by multiparallel sequencing, performed on tissues of Mdr2-WT (FVB.129P2) livers, Mdr2-KO (FVB.129P2-Abcb4tm1Bor/J) inflamed livers or hepatocarcinoma nodules from Mdr2-KO livers. All samples have been treated with clodronate liposomes to prevent sample contamination by liver macrophages
 
Contributor(s) Collino A, Ghisletti S, Termanini A, Natoli G
Citation(s) 29734330
Submission date Apr 28, 2016
Last update date May 15, 2019
Contact name Alberto Termanini
E-mail(s) termanini@me.com
Organization name Istituto Clinico Humanitas
Lab Bioinformatic Unit
Street address Via Manzoni, 113
City Rozzano
State/province MI
ZIP/Postal code 20089
Country Italy
 
Platforms (1)
GPL13112 Illumina HiSeq 2000 (Mus musculus)
Samples (16)
GSM2136886 134501_WT_CL_TR_H3K27Ac
GSM2136887 129296_WT_CL_TR_H3K27Ac
GSM2136888 130747_WT_CL_TR_H3K27Ac
This SubSeries is part of SuperSeries:
GSE80777 Characterization of a spontaneous model of inflammation-derived liver cancer
Relations
BioProject PRJNA319967
SRA SRP074135

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE80775_RAW.tar 7.1 Mb (http)(custom) TAR (of BED)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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