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| Status |
Public on Aug 25, 2017 |
| Title |
Murine mesenchymal stem/progenitor cells (MSPC): Ptpn11+/+ MSPC vs. Ptpn11E76K/+ MSPC |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Transcriptional profiling of mouse mesenchymal stem/progenitor cells (MSPC) comparing control Ptpn11+/+ MSPC with Ptpn11E76K/+ MSPC. By obtaining 20 million reads of sequence from two pair, we confirmed our cytokine/chemokine array data and quantitative ELISA data from both mouse and patient-derived specimens. CCL3, CCL12, CCL4, and CXCL12 (SDF-1) were aberrantly produced by Ptpn11 mutated MSPCs
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| Overall design |
Examination of mouse Ptpn11E76K/+ mesenchymal stem/progenitor cells (MSPC) transcriptional profiling compared to control Ptpn11+/+ MSPC, freshly isolated from Ptpn11E76K/+/Nestin and Ptpn11+/+/Nestin mice. Two replicate per array.
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| Contributor(s) |
Dong L, Qu C |
| Citation(s) |
27783593 |
| |
| Submission date |
May 11, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
LEI Dong |
| E-mail(s) |
lei.dong@emory.edu
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| Organization name |
Emory University
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| Street address |
1760 Haygood Drive NE, HSRB E3642
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| City |
Atlanta |
| ZIP/Postal code |
30322 |
| Country |
USA |
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| Platforms (1) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA321260 |
| SRA |
SRP074829 |
