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| Status |
Public on May 18, 2017 |
| Title |
NTRK3 kinase fusions in melanocytic tumors |
| Organism |
Homo sapiens |
| Experiment type |
Genome variation profiling by genome tiling array
|
| Summary |
We analyzed the copy number profiles of clinical samples of diagnostically difficult melanocytic tumors. Of 1202 cases, 22 cases demonstrated relative gain of the 5' portion of NTRK3. We further performed DNA or RNA sequencing on 12 of these cases and identified ETV6-NTRK3, MYO5A-NTRK3 and MYH9-NTRK3 fusions in the 8 cases in this cohort.
Analysis of genomic copy number of melanocytic tumors versus commericial pooled normal control.
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| |
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| Overall design |
Select cases from clinical array comparative genomic hybridization with confirmed NTRK3 fusions.
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| |
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| Contributor(s) |
Yeh I |
| Citation missing |
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| |
| Submission date |
May 19, 2016 |
| Last update date |
May 19, 2017 |
| Contact name |
Iwei Yeh |
| E-mail(s) |
Iwei.Yeh@ucsf.edu
|
| Organization name |
UCSF
|
| Department |
Dermatology
|
| Lab |
Bastian
|
| Street address |
1701 Divisadero St. Ste 280
|
| City |
San Francisco |
| State/province |
California |
| ZIP/Postal code |
94115 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL10123 |
Agilent-022060 SurePrint G3 Human CGH Microarray 4x180K (Feature Number version) |
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| Samples (8)
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|
| Relations |
| BioProject |
PRJNA322143 |
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