|
| Status |
Public on Dec 26, 2018 |
| Title |
Identification of novel recurrent ETV6-IGH fusions in primary central nervous system lymphoma using high throughput RNA sequencing |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We provide a novel gene fusion (ETV6-IgH) involving a truncation of ETV6 and leading to haploinsuffiency of ETV6 expression. ETV6-IgH is a new potential surrogate marker of PCNSL with favorable prognosis
|
| |
|
| Overall design |
We have performed RNA-Seq in 6 PCNSL patients and we have pinpointed several new chimeric transcripts
|
| |
|
| Contributor(s) |
Bruno A, Alentorn A |
| Citation(s) |
29432597 |
| |
| Submission date |
May 24, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Pierre de la Grange |
| E-mail(s) |
pierre.delagrange@genosplice.com
|
| Organization name |
GenoSplice technology
|
| Department |
Paris Biotech Santé
|
| Street address |
29, rue du Faubourg Saint-Jacques
|
| City |
Paris |
| ZIP/Postal code |
75014 |
| Country |
France |
| |
|
| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA322631 |
| SRA |
SRP075647 |
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