|
| Status |
Public on May 09, 2008 |
| Title |
Profiling of MCF-7 cells treated with proteasome inhibitor MG132 and either dexamethasone or 17b-estradiol |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
The objective of the study was to investigate the effect of proteasome inhibition on glucocorticoid and estrogen receptor regulated gene expression.
Keywords: Transcriptional profiling, Proteasome inhibitors, gene expression, steroid receptor
|
| |
|
| Overall design |
MCF-7 cells were treated with proteasome inhibitor (MG132), dexamethasone, 17b-estradiol or MG132 plus dexamethasone or MG132 plus 7b-estardiol. Control cells were not treated. RNA was collected from 2 biological experiments.
|
| |
|
| Contributor(s) |
Kinyamu HK, Archer TK |
| Citation(s) |
18381591 |
| Submission date |
Jul 05, 2007 |
| Last update date |
Jun 29, 2016 |
| Contact name |
NIEHS Microarray Core |
| E-mail(s) |
microarray@niehs.nih.gov, liuliw@niehs.nih.gov
|
| Organization name |
NIEHS
|
| Department |
DIR
|
| Lab |
Microarray Core
|
| Street address |
111 T.W. Alexander Drive
|
| City |
RTP |
| State/province |
NC |
| ZIP/Postal code |
27709 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL885 |
Agilent-011521 Human 1A Microarray G4110A (Feature Number version) |
|
| Samples (20)
|
|
| Relations |
| BioProject |
PRJNA101425 |
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