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| Status |
Public on Sep 12, 2016 |
| Title |
Fetal Brain lesions after subcutaneous inoculation of Zika virus in a pregnant nonhuman primate |
| Organism |
Macaca nemestrina |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
ZIKV was inoculated (strain FSS13025, Cambodia 2010) subcutaneously at five separate locations on the forearms, each with 107 plaque-forming units (PFU) into a healthy pregnant pigtail macaque at 119 days gestation (~28 weeks human pregnancy) to test directly whether ZIKV causes fetal brain injury.
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| Overall design |
Brain tissues from dam and fetus at necropsy (day 43 post-inoculation) were sequenced. A pigtail macaque brain sample from the Non-Human Primate Reference Transcriptome Project (NHPRTR.org) was used as a control
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| Contributor(s) |
Waldorf KA, Gale M Jr, Stencel-Baerenwald JE, Green R, Tisoncik-Go J |
| Citation(s) |
27618651 |
| |
| Submission date |
Jul 20, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Michael Gale, Jr |
| E-mail(s) |
uw_galelab_geo@uw.edu
|
| Organization name |
University of Washington
|
| Department |
Immunology
|
| Street address |
750 Republican St. E360, Box 358059
|
| City |
Seattle |
| State/province |
Washington |
| ZIP/Postal code |
98109 |
| Country |
USA |
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| Platforms (1) |
| GPL22173 |
Illumina NextSeq 500 (Macaca nemestrina) |
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| Samples (3) |
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| Relations |
| BioProject |
PRJNA330665 |
| SRA |
SRP078986 |
