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| Status |
Public on May 05, 2017 |
| Title |
Expression data from human primary skeletal muscle myotubes treated with aldosterone, spironolactone, eplerenone, mifepristone, prednisolone or vehicle |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
To define the direct gene expression changes in normal human skeletal muscle with mineralocorticoid and glucocorticoid receptor agonist and antagonist treatment.
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| Overall design |
18 total samples were analyzed. 3 biological replicates for each of the following treatment groups were included: 1) aldosterone; 2) spironolactone; 3) vehicle (DMSO); 4) eplerenone; 5) mifepristone; 6) prednisolone. Pairwise comparison between groups were carried out and a fold-change ≥2 were selected.
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| Contributor(s) |
Rafael-Fortney JA, Chadwick JA |
| Citation(s) |
28432191 |
| Submission date |
Jul 29, 2016 |
| Last update date |
Oct 29, 2018 |
| Contact name |
Jill Rafael-Fortney |
| E-mail(s) |
rafael-fortney.1@osu.edu
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| Organization name |
The Ohio State University
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| Department |
Physiology & Cell Biology
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| Lab |
410 Hamilton Hall
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| Street address |
1645 Neil Ave
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| City |
Columbus |
| State/province |
OH |
| ZIP/Postal code |
43210 |
| Country |
USA |
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| Platforms (1) |
| GPL17586 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
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| Samples (18)
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| GSM2255604 |
human myotubes, aldosterone treated, biological rep 1 |
| GSM2255605 |
human myotubes, aldosterone treated, biological rep 2 |
| GSM2255606 |
human myotubes, aldosterone treated, biological rep 3 |
| GSM2255607 |
human myotubes, spironolactone treated, biological rep 1 |
| GSM2255608 |
human myotubes, spironolactone treated, biological rep 2 |
| GSM2255609 |
human myotubes, spironolactone treated, biological rep 3 |
| GSM2255610 |
human myotubes, untreated/vehicle-treated, biological rep 1 |
| GSM2255611 |
human myotubes, untreated/vehicle-treated, biological rep 2 |
| GSM2255612 |
human myotubes, untreated/vehicle-treated, biological rep 3 |
| GSM2255613 |
human myotubes, eplerenone treated, biological rep 1 |
| GSM2255614 |
human myotubes, eplerenone treated, biological rep 2 |
| GSM2255615 |
human myotubes, eplerenone treated, biological rep 3 |
| GSM2255616 |
human myotubes, mifepristone treated, biological rep 1 |
| GSM2255617 |
human myotubes, mifepristone treated, biological rep 2 |
| GSM2255618 |
human myotubes, mifepristone treated, biological rep 3 |
| GSM2255619 |
human myotubes, prednisolone treated, biological rep 1 |
| GSM2255620 |
human myotubes, prednisolone treated, biological rep 2 |
| GSM2255621 |
human myotubes, prednisolone treated, biological rep 3 |
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| This SubSeries is part of SuperSeries: |
| GSE84992 |
Expression data from human primary skeletal muscle myotubes treated with aldosterone alone or in combination |
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| Relations |
| BioProject |
PRJNA335846 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE84990_RAW.tar |
432.1 Mb |
(http)(custom) |
TAR (of CEL, CHP) |
| Processed data included within Sample table |
| Processed data provided as supplementary file |
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