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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Sep 22, 2016 |
| Title |
RNA-seq analysis of livers of mice fed a high fat diet with and without administration of an inhibitor of the ileal bile acid uptake transporter ASBT |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
The study was designed to determine the effect of inhibition of ileal bile acid uptake on hepatic gene expression in high fat diet induced hepatic steatosis in mice
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| Overall design |
RNA-seq profiling was performed on liver tissues of mice fed a chow diet, a high-fat diet plus 0.2% (w/w) cholesterol (HFD), and the HFD plus the ASBT-inhibitor SC-435 (0.006%), for 16 weeks.
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| Contributor(s) |
Rao A, Kosters A, Mells J, Zhang W, Setchell K, Amanso A, Wynn G, Xu T, Keller B, Yin H, Banton S, Jones D, Wu H, Dawson P, Karpen S |
| Citation(s) |
27655848 |
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| Submission date |
Jul 29, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Astrid Kosters |
| E-mail(s) |
astrid.kosters@emory.edu
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| Organization name |
Emory University
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| Street address |
1760 Haygood Drive
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| City |
Atlanta |
| State/province |
Georgia |
| ZIP/Postal code |
30322 |
| Country |
USA |
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| Platforms (1) |
| GPL15103 |
Illumina HiSeq 1000 (Mus musculus) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA335841 |
| SRA |
SRP080330 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE84994_Rao_et_al_RNA-Seq_RPKM_data.xlsx |
23.1 Mb |
(ftp)(http) |
XLSX |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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