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Status |
Public on Aug 10, 2016 |
Title |
Comparison of RNA Pol II localization in the genomes of sig-7 (RNAi) vs WT C. elegans early stage embryos |
Organism |
Caenorhabditis elegans |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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Summary |
RNAi targeting a conserved C. elegans cyclophilin, sig-7, causes defective development and embryonic arrest consistent with a global defect in transcription. The goal of this study was to compare the location of RNA Pol II in sig-7(RNAi) embryos to the localization in L4440/RNAi control embryos to examine the global effect of loss of sig-7 on RNA Pol II regulation and its distribution within gene bodies
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Overall design |
anti-AMA-1 ChIP in 2 replicates each of sig-7(RNAi) and RNAi control early stage embryos
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Contributor(s) |
Kelly WG, Ahn J, Rechtsteiner A, Strome S |
Citation missing |
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Submission date |
Aug 10, 2016 |
Last update date |
May 15, 2019 |
Contact name |
Susan Strome |
E-mail(s) |
sstrome@ucsc.edu
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Organization name |
UC Santa Cruz
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Department |
MCD Biology
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Street address |
1156 High St
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City |
Santa Cruz |
State/province |
CA |
ZIP/Postal code |
95064 |
Country |
USA |
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Platforms (1) |
GPL13657 |
Illumina HiSeq 2000 (Caenorhabditis elegans) |
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Samples (8)
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This SubSeries is part of SuperSeries: |
GSE85445 |
HTS comparison of sig-7 (RNAi) vs WT C. elegans early stage embryos |
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Relations |
BioProject |
PRJNA338466 |
SRA |
SRP081235 |