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| Status |
Public on Dec 09, 2004 |
| Title |
Differential expression of Aspergillus genes as a result of disrupting maf1 |
| Organism |
Aspergillus flavus |
| Experiment type |
Expression profiling by array
|
| Summary |
We identified a 14-3-3 homolog (maf1) in an EST library made under conditions conducive to aflatoxin biosynthesis. Disruption of this gene in A. flavus by site directed mutagenesis abolished aflatoxin production. The maf1 mutant was morphologically similar to wild type but had reduced conidiation and growth on some media. DNA expression analysis of the wild type and maf1 mutant revealed that the mutation affected the expression profile of a set of genes associated with aflatoxin production.
Keywords = Aspergillus
Keywords = aflatoxin
Keywords = 14-3-3
Keywords: repeat sample
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| Contributor(s) |
Fakhoury AM, Payne GA |
| Citation missing |
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| Submission date |
Dec 09, 2003 |
| Last update date |
Mar 02, 2012 |
| Contact name |
Ahmad Fakhoury |
| E-mail(s) |
amfakhou@siu.edu
|
| Phone |
919-515-6995
|
| Organization name |
North Carolina State University
|
| Department |
Plant Pathology
|
| Lab |
Payne
|
| Street address |
|
| City |
Raleigh |
| State/province |
NC |
| ZIP/Postal code |
27695 |
| Country |
USA |
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| Platforms (1) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA87877 |
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