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Series GSE86447 Query DataSets for GSE86447
Status Public on Sep 06, 2019
Title RTEL1 modulates H3 occupancy in heterochromatic regions and acts synergistically with MET1/DDM1 to maintain genome integrity
Organism Arabidopsis thaliana
Experiment type Methylation profiling by high throughput sequencing
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Summary RTEL1 mainly mediates histone H3 occupancy in heterochromatic regions and functions in parallel with DDM1 and MET1 to maintain genome integrity.
 
Overall design Examine DNA methylation, histone modification and gene expression changes by whole-genome bisulfite sequencing; RNA sequencing; H3K27me3-, H3K4me3-, H3K9me2-, H3-ChIP-sequencing in L119 and rtel1-3 mutant
 
Contributor(s) Zhao X, Cheng J, Wang J, Meng J, Jin D, Zhao X, Zhu J, Gong Z
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Sep 06, 2016
Last update date Sep 08, 2019
Contact name Jinkui Cheng
E-mail(s) chengjinkui@cau.edu.cn
Organization name China Agricultural University
Lab Zhizhong Gong
Street address No.2 Yuanmingyuan West Road
City Beijing
ZIP/Postal code 100193
Country China
 
Platforms (2)
GPL13222 Illumina HiSeq 2000 (Arabidopsis thaliana)
GPL17639 Illumina HiSeq 2500 (Arabidopsis thaliana)
Samples (20)
GSM2302839 L119_bisulfite sequencing-R1_R2
GSM2302840 rtel1-3_bisulfite sequencing-R1_R2
GSM2302841 L119_RNA_rep1_R1_R2
Relations
BioProject PRJNA341942
SRA SRP086609

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE86447_RAW.tar 320.5 Mb (http)(custom) TAR (of BED, TXT)
GSE86447_RNA-seq-rtel1-3-downregulated.xlsx 1.1 Mb (ftp)(http) XLSX
GSE86447_RNA-seq-rtel1-3-upregulated.xlsx 1.1 Mb (ftp)(http) XLSX
GSE86447_RNA-seq-rtel1-3-zebularine-downregulated.xlsx 21.4 Kb (ftp)(http) XLSX
GSE86447_RNA-seq-rtel1-3-zebularine-upregulated.xlsx 32.4 Kb (ftp)(http) XLSX
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

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