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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Jan 11, 2008 |
| Title |
Gene expression in mouse white adipose tissue |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Trans-10, Cis-12 conjugated linoleic acid (t10c12 CLA) causes fat loss in mouse white adipose tissue (WAT). The early transcriptome changes in WAT were analyzed using high-density microarrays to better characterize the signaling pathways responding to t10c12 CLA. Their gene expression responses between 4 to 24 hr after treatment showed a common set of early gene expression changes indicative of an integrated stress response (ISR).
Keywords: control/treatment time course
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| Overall design |
Mouse WAT RNA for each time point was isolated from two control and two treatment samples for analysis on four microarrays. The two control and two treatment samples consisted of RP tissues from 5 pooled mice for each sample, requiring a total of twenty mice for the four samples taken at each time point.
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| Contributor(s) |
LaRosa C, Riethoven JM, Chen H, Xia Y, Zhou Y, Chen M, Miner J, Fromm ME |
| Citation(s) |
17878318 |
| Submission date |
Aug 03, 2007 |
| Last update date |
Feb 11, 2019 |
| Contact name |
Jean-Jack M. Riethoven |
| E-mail(s) |
jeanjack@unl.edu
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| Organization name |
University of Nebraska-Lincoln
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| Department |
Beadle Center for Biotechnology
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| Lab |
Bioinformatics Core Research Facility
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| Street address |
1901 Vine Street
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| City |
Lincoln |
| State/province |
NE |
| ZIP/Postal code |
68588-0665 |
| Country |
USA |
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| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
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| Samples (12)
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| GSM215232 |
mouse white adipose tissue, CLA fed, T1, biological rep1 |
| GSM215233 |
mouse white adipose tissue, CLA fed, T1, biological rep2 |
| GSM215234 |
mouse white adipose tissue, LA fed (control), T1, biological rep1 |
| GSM215235 |
mouse white adipose tissue, LA fed (control), T1, biological rep2 |
| GSM215236 |
mouse white adipose tissue, CLA fed, T2, biological rep1 |
| GSM215237 |
mouse white adipose tissue, CLA fed, T2, biological rep2 |
| GSM215238 |
mouse white adipose tissue, LA fed (control), T2, biological rep1 |
| GSM215239 |
mouse white adipose tissue, LA fed (control), T2, biological rep2 |
| GSM215240 |
mouse white adipose tissue, CLA fed, T3, biological rep1 |
| GSM215241 |
mouse white adipose tissue, CLA fed, T3, biological rep2 |
| GSM215242 |
mouse white adipose tissue, LA fed (control), T3, biological rep1 |
| GSM215243 |
mouse white adipose tissue, LA fed (control), T3, biological rep2 |
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| This SubSeries is part of SuperSeries: |
| GSE11384 |
Trans-10, cis-12 conjugated linoleic acid activates the integrated stress response pathway in adipocytes |
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| Relations |
| BioProject |
PRJNA109031 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE8679_12h_RosettaResolver_processed_ratio.xls |
3.0 Mb |
(ftp)(http) |
XLS |
| GSE8679_24hr_RosettaResolver_processed_ratio.xls |
3.0 Mb |
(ftp)(http) |
XLS |
| GSE8679_4hr_RosettaResolver_processed_ratio.xls |
3.0 Mb |
(ftp)(http) |
XLS |
| GSE8679_RAW.tar |
38.6 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
| Processed data are available on Series record |
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