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Series GSE86846 Query DataSets for GSE86846
Status Public on Sep 13, 2016
Title Global Regulation of Alternative RNA Splicing by the SR-Rich Protein RBM39
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary RBM39 is extensively involved in alternative splicing of RNA and helps regulate transcript levels. RBM39 may modulate alternative splicing similarly to U2AF65 by either directly binding to RNA or recruiting other splicing factors, such as U2AF65.
 
Overall design RNA extracted from wild-type and RBM39-deficient human breast adenocarcinoma MCF-7 cells was subjected to RNA-Seq, and alternative splicing events in the two cell types were analyzed and compared.
 
Citation(s) 27354116
Submission date Sep 12, 2016
Last update date May 15, 2019
Contact name Mai Sanyue
E-mail(s) syue_356@163.com
Organization name Beijing Institute of Biotechnology
Street address 27 Taiping Rd, Haidian District
City Beijing
ZIP/Postal code 100850
Country China
 
Platforms (1)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
Samples (3)
GSM2309313 wild-type MCF-7 cells
GSM2309314 RBM39-knockdown MCF-7 cells
GSM2309315 U2AF65-knockdown MCF-7 cells
Relations
BioProject PRJNA342707
SRA SRP089740

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE86846_All_Fragments.xls.gz 861.4 Kb (ftp)(http) XLS
GSE86846_All_UQFPKM.xls.gz 1.4 Mb (ftp)(http) XLS
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Raw data are available in SRA
Processed data are available on Series record

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