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| Status |
Public on Sep 28, 2016 |
| Title |
Transcript profiling in the liver of early-lactating dairy cows fed conjugated linoleic acid |
| Organism |
Bos taurus |
| Experiment type |
Expression profiling by array
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| Summary |
In the present study, transcript profiling was carried out in the liver samples from wk 5 of lactation in order to identify genes and pathways regulated by rumen-protected CLA during early lactation. The first wks after parturition represent a critical phase in the productive cycle of high-yielding dairy cows because the liver experiences pronounced metabolic and inflammatory stress which increases the risk to develop liver-associated diseases, such as fatty liver and ketosis.
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| Overall design |
For microarray analysis, RNA pools (n = 5) each for the CLA group and the control group were prepared. Each RNA pool comprised RNA from 4 different cows. The RNA pools were used for hybridization to the GeneChip® Bovine Genome Array (Affymetrix, High Wycombe, UK).
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| Contributor(s) |
Ringseis R, Eder K |
| Citation(s) |
27766206 |
| |
| Submission date |
Sep 27, 2016 |
| Last update date |
Dec 28, 2016 |
| Contact name |
Robert Ringseis |
| E-mail(s) |
robert.ringseis@ernaehrung.uni-giessen.de
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| Organization name |
JLU Gießen
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| Department |
Institute of Animal Nutrition and Nutrition Physiology
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| Street address |
Heinrich-Buff-Ring 26-32
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| City |
Gießen |
| ZIP/Postal code |
35390 |
| Country |
Germany |
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| Platforms (1) |
| GPL2112 |
[Bovine] Affymetrix Bovine Genome Array |
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| Samples (10)
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| Relations |
| BioProject |
PRJNA344645 |
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