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| Status |
Public on Aug 28, 2007 |
| Title |
Transcriptional pathways associated with skeletal muscle disuse atrophy in humans |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Disuse atrophy is a common clinical phenomenon which significantly impacts muscle function and activities of daily living. In this study, we did expression profiling to identify transcriptional pathways associated with muscle remodeling in a clinical model of disuse.
Keywords: Differentiation design
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| |
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| Overall design |
28 Skeletal muscle biopsies from the medial gastrocnemius in patients with an ankle fracture (4 patients, 8 profiles) and from healthy volunteers (2 subjects, 4 profiles) subjected to 4-11 days of mobilization, as well as from the non-immobilized contralateral legs (16 profiles).
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| |
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| Contributor(s) |
Yiwen C |
| Citation(s) |
17804603 |
| |
| Submission date |
Aug 24, 2007 |
| Last update date |
Oct 01, 2019 |
| Contact name |
Eric P Hoffman |
| E-mail(s) |
ericphoffman@gmail.com
|
| Organization name |
Binghamton University - SUNY
|
| Department |
Pharmaceutical Sciences
|
| Street address |
PO Box 6000
|
| City |
Binghamton |
| State/province |
NY |
| ZIP/Postal code |
13902 |
| Country |
USA |
| |
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| Platforms (2) |
| GPL91 |
[HG_U95A] Affymetrix Human Genome U95A Array |
| GPL8300 |
[HG_U95Av2] Affymetrix Human Genome U95 Version 2 Array |
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| Samples (28)
|
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| Relations |
| BioProject |
PRJNA102241 |
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