|
| Status |
Public on Oct 19, 2016 |
| Title |
The development of Drosophila melanogaster during space flight |
| Organism |
Drosophila melanogaster |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
In prospective human exploration of outer space, the need to maintain a species over several generations under changed gravity conditions may arise. This paper reports the analysis of the third generation of fruit fly Drosophila melanogaster obtained during the 44.5-day space flight (Foton-M4 satellite, 2014, Russia), followed by the fourth generation on Earth and the fifth generation under conditions of a 12-day space flight (2014, in the Russian Segment of the ISS). The obtained results show that it is possible to obtain the third-fifth generations of a complex multicellular Earth organism under changed gravity conditions (in the cycle “weightlessness – Earth – weightlessness”), which preserves fertility and normal development. However, there were a number of changes in the expression levels and content of cytoskeletal proteins that are the key components of the spindle apparatus and the contractile ring of cells.
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| |
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| Overall design |
Examination of drosophila genes expression change during space flight by RNA-Seq technique
|
| |
|
| Contributor(s) |
Ogneva IV, Belyakin SN, Sarantseva SV |
| Citation(s) |
27861601 |
| |
| Submission date |
Oct 18, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Daniil Maksimov |
| E-mail(s) |
vift@mail.ru
|
| Organization name |
MCB NSC RAS
|
| Lab |
Genomics lab
|
| Street address |
Lavrentjeva ave., 8/2
|
| City |
Novosibirsk |
| ZIP/Postal code |
630090 |
| Country |
Russia |
| |
|
| Platforms (1) |
| GPL16479 |
Illumina MiSeq (Drosophila melanogaster) |
|
| Samples (10)
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|
| Relations |
| BioProject |
PRJNA348832 |
| SRA |
SRP091700 |
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